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Monday, November 1, 2010

Anti-Aging: Retinol



Introduction:

Retinol is part of a class of chemical compounds called 'Retinoids' which are structurally similar to Vitamin A.


Terminology/Ingredients:

Examples of the compound include: retinol, tretinoin, isotretinoin, tazarotene.

Pro-retinol products (chemicals which are broken down to retinol) include: Retinyl Actate and Retinyl Palmitate.


Indications:

-Acne
-Wrinkles
-Age spots/ hyperpigmentation
-Sun damaged skin


Mechanism of action:

Retinol is thought to increase collagen production by stimulating skin cells called fibroblasts which aids healing and pushes the 'damaged and pigmented skin cells' to the top of the skin to allow to be 'sloughed' off providing a brightening effect. Meanwhile it also inhibits the enzymes that cause skin cell destruction.


Evidence-based:

Many studies have been performed but the most renowned is from the University of Michigan which reported in the Journal Archives of Dermatology evidence to support that 0.1% tretinoin significantly reduced wrinkles and roughness after 8-12 months of use.


Packaging:

Higher doses are dermatologist prescribed only. However, there are lower dosed retinol in moisturisers/ serums sold in both drugstores and departmental stores. Retinol must be packaged properly to ensure it remains stable for continued and effective use as it is light and air-sensitive.


Adverse effects:

Dry flakiness and sensitivity.

Sun exposure can cause increased skin sensitivity.


Interactions:

Can work synergistically with AHA/BHA products for better penetration through the epidermis of the skin.


Controversies:

A former lawyer now turned cosmetic scientist argues that retinoids actually causes aging by increasing moisture loss at the outermost layer of the skin.


Products I might purchase:

RoC Multi-Correxion Night Treatment

Olay Pro-X Deep Wrinkle Treatment





Important Disclaimer: None of the above advice can be a substitute for medical or professional skin care advice - please only consult qualified general medical and/ or dermatology physicians for serious skin complaints. The information is not sponsored by manufacturers here but may reflect their claims and this site cannot be held responsible for such claims made.


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